The use of 99mTc-MIBI scanning in multiple myeloma

99mTc-MIBI scintigraphy in the diagnosis of multiple myeloma.

POLSKIE ARCHIWUM MEDYCYNY WEWNĘTRZNEJ 2016; 126 (3) MM is characterized by malignant proliferation of clonal plasma cells and excessive formation of monoclonal immunoglobulin.1 99mTc-MIBI is a radiotracer commonly used in myocardial perfusion imaging (FIGURE 1C). In literature, there have been reports on the use of 99mTc-MIBI in the diagnosis of MM since 1996.2 In a multicenter study conducted ...

18F-FDG PET/CT, 99mTc-MIBI, and MRI in evaluation of patients with multiple myeloma.

UNLABELLED New imaging techniques have been introduced to assess the extent and severity of disease in multiple myeloma (MM) patients. The aim of our study was to compare newer imaging modalities-such as (18)F-FDG PET/CT, (99m)Tc-methoxyisobutylisonitrile ((99m)Tc-MIBI) scintigraphy, and MRI-to assess their relative contribution in the evaluation of MM patients at diagnosis. METHODS Thirty-th...

99mTc-MIBI whole body scintigraphy and P-glycoprotein for the prediction of multiple drug resistance in multiple myeloma patients.

Multi-drug resistance (MDR) is a major challenge in the treatment of multiple myeloma (MM). There is low sensitivity of technetium-99m methoxy isobutyl isonitrile ((99m)Tc-MIBI) whole body scan (WBS) in the detection of active MM lesions, because (99m)Tc-MIBI is washed out from malignant cells in the presence of P-glycoprotein (PGP). The objective of the present cohort study was to evaluate of ...

The value of Tc-99m MIBI scintigraphy in active diseases and remission phase of multiple myeloma [Persian]

99mTc-MIBI scintigraphy in musculoskeletal tumors.

UNLABELLED The aim of this study was to assess the value of 99mTc-hexakis2-methoxyisobutylisonitrile (MIBI) scintigraphy in patients with clinical and radiologic features of primary or metastatic musculoskeletal tumors. METHODS The scintigraphic findings for 84 patients were compared with the surgical and histologic findings. Each patient underwent three-phase bone scanning with 99mTc-methyle...